Aromatose inhibitor does it increase height
Analysis
Aromatase inhibitors (AIs) have been studied for their potential to increase height by delaying the fusion of growth plates, a process regulated by estrogen. Several sources suggest that AIs can slow epiphyseal maturation and may improve short-term growth outcomes, particularly in boys with growth disorders or short stature. However, the evidence for a significant increase in final adult height remains inconclusive and limited, with some studies showing no clear benefit on ultimate height. Most data come from small or preliminary studies, often without long-term follow-up. Thus, while AIs may have some effect on height progression during puberty, their ability to reliably increase final adult height is not definitively proven.
Sources
Indicates AIs may slow growth plate fusion but cautions remain about ultimate height effects.
Supports deceleration of growth plate fusion but does not confirm final height increase.
Discusses potency differences in AIs but does not confirm height increase.
Notes short-term growth improvement but no evidence for increased final height.
Suggests predicted adult height may increase but based on hypothesis testing.
Explains estrogen’s role in growth plate closure, implying AIs could affect height.
Reports potential beneficial effects on height potential but limited scope.
Mentions outcome analyses but does not confirm definitive height increase.
Refers to subanalysis suggesting some effect but not conclusive.
States AIs may boost height in short pubertal boys, often combined with growth hormone, but evidence is not definitive.
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